Endocrine Abstracts

Background: Metabolic syndrome has been introduced to increase the incidence of cardiovascular diseases and type 2 diabetes mellitus. Our aim of this study was to investigate the relation for normal fasting plasma glucose levels and metabolic syndrome in normoglycemic adults.Methods: The study subjects consisted of 636 individuals who visited the Center for Health Promotion in Pusan National University Hospital for a medical checkup in 2002 to 2005. Amon...

Introduction: Type 2 diabetes (T2D) has increased in youth and complications rates may be higher than type 1 diabetes (T1D).Aims: To estimate the prevalence of complications and hypertension in youth with type 2 diabetes and compare complication rates between T2D and T1D.Design and methods: Systematic review and meta-analysis of observational studies, analysed with random effects models.Data sources: Medline ...

Introduction: Activating somatic mutation of the BRAF gene (V600E) has been identified as the most common genetic event in papillary thyroid carcinoma (PTC) with a variable frequency (32–87%) in various races by different methods.In this study, we report the genetic analysis of BRAF mutation in a Korean cohort of 211 PTC by peptide nucleic acid clamp real-time PCR.Methods: PNA clamp real-time PCR was applied for BRAF analysis ...

Aims: We investigated the interrelationship between HbA1c, fructosamine, glycoalbumin (GA), 1,5-anhydroglucitol (1,5-AG) with glycemic variability data from continuous glucose monitoring system (CGMS).Methods: Seventy diabetic patients (mean age of 54 years including seven type 1 diabetes mellitus subjects) were enrolled, and all wore a CGMS for 72 hours. For the parameters of glucose excursion, mean glucose, standard deviation (SD) of glucose, the area ...

Introduction: Widespread availability of internet makes it an attractive communication tool among patients and providers. However, the clinical benefit of telemedical support on diabetes care remains inconclusive. This study is to determine whether an internet based mentoring program can improve glycemic control in type 1 diabetes (T1DM) patients with inadequate glycemic control.Methods: Patients with T1DM on intensive insulin therapy and with HbA1c &#x2...

Introduction: The natural history of primary hypophysitis is incompletely understood and best treatment remains controversial.Methods: We performed a retrospective study of 19 patients (mean age of 47 years, fifteen women and four men) who were diagnosed with primary hypophysitis in Samsung Medical Center in Seoul, Korea, from January 2001 to October 2011.Results: Two patients had recent pregnancy and underlying autoimmunity. Most ...